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dc.contributor.authorДудук, Н. И.
dc.date.accessioned2017-07-12T12:52:20Z
dc.date.available2017-07-12T12:52:20Z
dc.date.issued2014
dc.identifier.urihttp://rep.bsmu.by:8080/handle/BSMU/15390
dc.descriptionДудук, Н. И. Влияние холестаза матери на печень двухсуточных крысят и коррекция патологии урсодезоксихолевой кислотой = Influence of maternal cholestasis in the liver of two-day rat pups and correction this disturbance with ursodeoxycholic acid / Н. И. Дудук // БГМУ: 90 лет в авангарде медицинской науки и практики: сб. науч. тр. / М-во здравоохр. Респ. Беларусь, Бел. гос. мед. ун-т; редкол. : А. В. Сикорский, О. К. Кулага. – Минск : ГУ РНМБ, 2014. – Вып. 4. – С. 80-83.ru_RU
dc.description.abstractThe purpose of research — to clarify the influence of maternal experimental cholestasis on liver development of a two-day offspring and the possibility to correct those violations by "Ursofalk". In this paper we used material from 30 inbred albino rats, histological, histochemical, morphometric and electronic microscopy methods of investigation. Under the influence of maternal cholestasis in the liver of two-day offspring the extention of sinusoid capillaries, in the cytoplasm of hepatocytes a reduction succinate dehydrogenase activity and increased activity of NADH — dehydrogenase was revealed. The development of significant ultrastructural disturbanses (lipid droplets disappear, increased heterogeneity of size and shape of mitochondria, increases number of lysosomes). Preparation "Ursofalk" partially restores the structure and metabolism of hepatocytes.ru_RU
dc.language.isoruru_RU
dc.publisherГУ РНМБru_RU
dc.subjectХолестазru_RU
dc.subjectЛабораторные животныеru_RU
dc.subjectКрысыru_RU
dc.titleВлияние холестаза матери на печень двухсуточных крысят и коррекция патологии урсодезоксихолевой кислотойru_RU
dc.title.alternativeInfluence of maternal cholestasis in the liver of two-day rat pups and correction this disturbance with ursodeoxycholic acidru_RU
dc.typeArticleru_RU


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