Особенности индивидуальной гемодинамики (по данным линейной регрессии параметров артериального давления) и функциональное состояние сосудов у практически здоровых молодых людей

Abstract

165 young patients at the age of 21-34 years (group of healthy normotensive individuals, n=120, and group of hypertensive patients, n=45) were examined by the QARBPP method (the quantitative analysis of relations of blood pressure parameters - the linear regression); the function of vessels, that is the endothelial function of vessels and pulse wave velocity (PWV) were investigated by the rheographic methods. Dysfunctional hemodynamic types (QARBPP-types) were revealed in 25.8% of healthy participants. The most frequently registered pathological type was diastolic dysfunctional type (DD): 20.0% in healthy participants, 51.1% in hypertensive patients, P<0.05. Normotensive individuals in DD-type had disturbances of the endothelial function more frequently, than those in the harmonious type (P<0.05), and their PWV was increased (11.4 m/s and 8.1 m/s respectively, Р=0,00). PWV in these healthy participants did not differ from PWV in hypertensive patients. The QARBPP method allows revealing the latent hemodynamic disturbances, such as dysfunctional hemodynamic types connected with the vessels dysfunction.