Диагностическая значимость биохимических маркеров при тромбоэмболии легочной артерии

Abstract

Analysis of 103 case histories of patients with pulmonary embolism was held. Changes in the level of cardiac enzymes (creatinekinase, troponin I) was investigated. Troponin exceeded 0.05 ng/ml in 33.3% of cases, CK-MB exceeded 24 IU/L in 42.7% of cases. Patients with ECG signs of thromboembolism CK-MB was elevated in 57.5%, within the normal range — in 42.5%, whereas in the absence of ECG changes in CK-MB was increased only 25.7% had normal — in 74.2% (p = 0.011). The incidence of cardiac enzyme levels depended on the caliber of embolized vessels: in patients with lesions of the small branches of the pulmonary artery was observed in the enzyme reaction 20.9% cases, the lesion middle branches — in 53.5% of cases (p = 0.10).