Предварительные результаты применения системы прогнозирования исходов тромболитической терапии у больных с инфарктом головного мозга с использованием критериев нейровизуализации

Abstract

Analysis of the case histories of patients with ischemic stroke (IS), which was carried out thrombolysis, was performed. For standardization and objectivization in data acquisition formalized medical history was developed. Data processing was carried out in accordance with conventional methods of variation statistics by the use of Microsoft Excel and STATISTICA. In consideration of the small number of observations, Spearman's rank correlation coefficient and the method of multiple linear regressions for statistical analysis were used. After analyzing 36 parameters including anamnestic, clinical, instrumental, laboratory and neuroimaging of formalized medical history, it was found statistically significant (p <0.05) effect of 8 ofthem on the outcome of IS after systemic thrombolysis. Each parameter, depending on its degree of manifestation, defined a score. The multiple linear regression coefficients allowed to determine the significance factor of each of the TLT predictors. This has made it possible to create a formula that quantifies the outcome of TLT.