Получение культур эндотелиальных клеток-предшественников из крови пациентов с лакунарными инфарктами мозга при церебральной микроангиопатии

Abstract

The cultures of late-outgrowth endothelial cells from peripheral blood of patients with acute lacunar stroke were isolated. The cultures in question possessed high proliferative capacity, endothelial phenotype (CD31+ KDR+ CD34+ CD144+) and a characteristic "cobblestone" morphology upon confluence. The isolation was successful in 71.43% of cases (5 out of 7 blood samples). The incidence of late-outgrowth colonies was 0.29±0.06 colonies per milliliter of blood in samples with successful isolation.