Распределение иммунореактивности к субстанции П и бомбезину в звездчатом ганглии человека при остром инфаркте миокарда

Abstract

By the method of indirect immunohistochemistry the distribution patterns of substance P (SP) and bombesin expression in human stellate ganglia after acute myocardial infarction were investigated. Up-regulation of both SP and bombesin-immunoreactivities was revealed. It was concluded that hypoxia and myocardial ischemia following acute myocardial infarction are the main inducing factor for the synthesis of SP and bombesin. The increase of SP and bombesin may provide regulatory and trophic support to the ischemic myocardium.