Prediction of acute toxicity of biologically active substances of Adonis Vernalis

Abstract

Nowadays pre-experimental researches in silico are gaining increasing use. Using in silico methods can be obtained preexperiment analysis of biologically active substances of both synthetic and natural origin. They give an opportunity to save time of research, to emphasize the areas of experimental tests and to identify the best ways to achieve the objectives. The GUSAR Acute Rat Toxic program provides an opportunity to predict acute toxic effects on rats by the in silico method, which is more humane than the classic method.