Comparative analysis of TLR4 expression on monocytes in interaction with isolates of Klebsiella pneumoniae isolated

Abstract

TLR4 is the main recognition receptor of K. pneumoniae, as it is able to recognize lipopolysaccharide present in the cytoplasmic membrane. Comparative analysis of TLR4 expression on immune cells when cultured with microorganisms will allow the relative pathogenic potential of the isolates to be assessed. This study presents the results of evaluation of the effects on monocytes of K. pneumoniae isolated from clinical material and environmental objects