Effect of UV irradiation on fluorescence and antioxidant properties of γ-globulins
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Дата
2022Автор
Sozarukova, M. M.
Chilikina, P. A.
Skachko, N. A.
Novikov, D. O.
Proskurnina, E. V.
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Ultraviolet blood irradiation is an alternative approach for the treatment of
infectious diseases of various etiologies and is a new immunomodulatory method. To
date, there are no data in the literature on the precise mechanisms of the effects of UV
radiation on various blood components, including proteins. The aim of the present
work was to analyze the fluorescent properties of γ-globulins after UVI exposure (254
nm) with simultaneous registration of their antioxidant profile by chemiluminescent
method in a model with alkylperoxyl radicals. We obtained that exposure of γ-globulins
to UV leads to a dose-dependent decrease in fluorescence and a more complex kinetic
curve of chemiluminescence due to the formation of products with stronger antioxidant
properties.
Библиографическое описание
Effect of UV irradiation on fluorescence and antioxidant properties of γ-globulins [Электронный ресурс] / M. M. Sozarukova [и др.] // Современные проблемы медицинской биохимии : сб. статей участников Междунар. науч.-практ. конф, посвящ. 85-летию проф. В.К. Кухты, Минск, 25 янв. 2022 г. / под ред. А. Д. Тагановича, Н. Н. Ковганко, В. В. Хрусталева. – Минск, 2022. – C. 273 – 276.